Bilateral keratoconus

bilateral  means both sided. bilateral keratoconus therefore means that both eyes are involved. Keratoconus is an asymmetric bilateral disease. Keratoconus means coning of the cornea. The clear front part of the eye is cornea. When internal pressure of the eye is able to overcome the resistance of the cornea, it leads to bulging of the cornea. This is termed as keratoConus. Usually one eye may be more involved. To the untrained eye this may be unilateral. But to Los Angeles keratoconus expert the second eye may still have subtle signs of keratoconus/


Tritia’s story

Tritia is a wonderful person who was suffering from not such a wonderful disease keratoconus. Here is her story in her own words.
This story is for educational purposes. A lot of patients in Los Angeles, California suffer from keratoconus. They do not have access to the latest information. Sometimes even the medical community is unaware of the latest technology in the hands of keratoconus experts of Beverly hills. So we want to spread information on intacs, cross linkage and other newer treatments directly to the people suffering from keratoconus.
Tritia is a warrior in this battle against keratoconus. She deserves our congratulations and continued support.

Happy New year and new intacs

2011 is going to be your year , reader. This year may your wishes be fulfilled. The light fill your life and be bestowed upon you. May keratoconus monster be tamed with intacs at the hands of Beverly hills intacs expert, Rajesh Khanna , MD .may the intacs change the shape of your eye quickly and push the cone up. 2011 will lead therefore to decreased higher order aberrations. Optically it would be a miracle. Visually it would be delightful. Functionally you would be more productive. So book your ticket to Los Angeles and fly, drive or bike to Beverly hills to improve the shape of your cornea ravaged by keratoconus.

Hormone and keratoconus

This study is from Clek or the collaborative longitudinal evaluation of keratoconus. It came from college of optometry in Ohio.
METHODS: The severity and progression of keratoconus in both men (M) and women were evaluated over a 4-year period that encompassed menopausal transition for hormone-active women (HA) and hormone-inactive women (HI). Four outcome measures were selected as indicators of the severity of keratoconus: high-contrast best-corrected visual acuity, low-contrast best-corrected visual acuity, the steep keratometric measurement, and corneal scarring (yes/no).

RESULTS: There were no statistically significant differences among the 3 groups (M, HA, and HI) in race, history of atopic disease, family history of keratoconus, or rigid contact lens wear in the right and left eyes. At baseline, there were no significant differences among the 3 groups in high-contrast best-corrected visual acuity, low-contrast best-corrected visual acuity, or steep keratometric reading. Progression of keratoconus, as assessed by changes in these 3 continuous variables, was equal for the 3 groups. M had more corneal scarring than did HA or HI; however, there was no progression of scarring for any of the groups.

CONCLUSION: Keratoconus progressed in both men and women, aged 48-59 years; however, there were no differences among the groups in progression.
So what we learn her is that if you live in Los Angeles and suffer from keratoconus, there is still a chance of scarring even if you are in your fourties. You need to see Los Angeles cornea expert . Dr Khanna has offices in Beverly hills and west lake village and helps residents of Los Angeles with management of keratoconus.

Genetics of keratoconus

Keratoconus (KC) is a bilateral, non-inflammatory, and progredient corneal ectasia that mostly occurs as a sporadic disorder, but it has long been recognized that a significant minority of patients also exhibit a family history. In Los Angeles in recent years several candidate genes such as VSX1 and SOD1 have been proposed, and some disease-causing mutations have been identified. Keratoconus research in united states has also focused on collagen genes, especially those that are differentially expressed in KC cornea. Alterations in COL4A3 and COL4A4 genes may be responsible for decreases in collagen types I and III, a feature often detected in Los angeles keratoconus.

Keratoconus in Singapore

<ins datetime="2010-12-22T14:45:58+00:Mean age of our patients was 29.5 ± 9.40 years on enrolment, 62.9% males, and the ethnic distribution was 60.3% Chinese, 13.8% Malays, and 9.5% Indians. Clinically-evident keratoconus was present in both eyes of 65 patients (56.0%) and unilateral keratoconus in 5 patients (4.3%). Five patients (4.3%) had a family history of keratoconus. The majority of patients were managed with contact lenses (60.8%) or glasses (24.5%). Eye-rubbing was common (68%) as were atopic conditions such as asthma (26.3%) and eczema (18.4%). Conical protrusion was the commonest sign (75.3%). The mean cylinder was higher in keratoconus eyes compared to keratoconus suspect eyes (-4.01 vs -1.27, p < 0.001) while best corrected VA was significantly poorer (0.19 vs 0.05, p < 0.001). Unaided VA was significantly worse with increasing age (p = 0.016)Baby interesting study from Singapore body chill and Dan has shown that candidate Glenys incidents and the EVA indication population is similar to dad falling in the distant countries like United States Navy studied the allegations of chemical message came to the hospital and found the average age was 30 years and did the range from 20 to 40 years in Singapore this phone does all the population 60% with Chinese & order for Indian origin photo at 5% off then had relatives quit being diagnosed with Canada calling us and butter under treatment most of the patients were meals and or lease sign in the station is depicted in photography laws go any further on vision of function questionnaire because found that activities of the living for affected more than what could have been simply the case for the kind of fish and they had so you give me a mix of common conclusion that keratoconus going to spend presence in early in the eastern hemisphere like a vested hemisphere me of the more commonly affected and it’s a disease that you fix both eyes read it just have I may have a small chance of suffering from the same disease keratoconus

India with Love

Hi this is Sh…. from Bangalore, India. I am Suffering from keratoconus since 2000. There has been a progression from left eye and now to right eye.. currently using piggyback lens for left eye.. cannot wear for more than 4-5 hours continuously..Suggest better methods

What causes keratoconus?

What causes keratoconus?

The causes of this condition are still unknown despite our familiarity with this disease. There have been many studies and there have been many theories.

One proposal suggests that orange county keratoconus depends on a defect in the development and genetic (about 7% of patients have relatives with keratoconus). This suggests that the consequence of an abnormality in growth, essentially a birth defect. Another is that Keratoconus is a degenerative condition. A third postulated that keratoconus is secondary to other diseases. A less accepted theory suggests it may be of endocrine origin.

The actual incidence of orange county keratoconus is not known. It is one of the most common afflictions of the eye but it is by no means a rare disease. Is estimated to occur once in every two thousand people. Usually the disease occurs in young people at puberty. It is found everywhere in the world without follow any geographical pattern, cultural or social acquaintance. Several sources suggest that keratoconus probably arises from a number of different factors: genetic, environmental or cell phone, no one can form the trigger that will initiate the disease. There are also doctors who associate the scratching keratoconus eyes. Often the patient has allergic rhinitis associated with keratoconus, which causes the eyes itch often. This can cause thinning of the cornea due to mechanical removal of epithelial cells.

The visual distortion experienced by the patients come from two sources, one being the irregular deformation of the surface of the cornea, and other scars formed at points of high curvature exposed. These factors act together to form regions on the cornea which projects an image into different regions of the retina and cause the symptoms of monocular diplopia or monocular poliplopia. The effect can worsen in low light because the pupil tends to dilate in order to receive more light, and thus further exposing the irregularities of the cornea. Scars seem to be an aspect of the degradation of the cornea, however, a large multi-center study conducted (Clek STUDY – Collaborative Longitudinal Evaluation of Keratoconus Study) suggests that the abrasion caused by contact lenses may increase the tendency of this finding on one factor above two, or more than double the chance of occurrence.

Recent studies have shown that orange county keratoconus corneas show signs of increased activity of proteases, a class of enzymes that break part of the collagen fibers in the corneal stroma, with a simultaneous significant reduction of the action of protease inhibitors. Other studies have suggested that the reduction of activity by the enzyme aldehyde dehydrogenase may be responsible for the creation of free radicals and oxidant species in the cornea. It is quite likely that whatever the pathogenic process, the damage caused by activities in the cornea resulting in reduction of its ultrasound pachymetry and weakening their resistance biomechanics.

A genetic predisposition for keratoconus has been observed, with the disease manifesting itself in certain families, and reported incidences of concordance in identical twins. The frequency of occurrence in close relatives is not clearly defined, although it is known that the incidence is considerably higher than in the general population, and studies have obtained estimates ranging between 6% and 19%. The gene responsible for keratoconus has not been identified: two large studies involving isolated communities homogenéticas contrary has indicated as causes of genetic disease mapped to chromosomes 16q and 20q. However, most genetic studies agree on a model autosome dominant hereditary. Keratoconus is also diagnosed more often in people with Down syndrome, although the reasons for this link have not yet been determined. Keratoconus has been associated with atopic diseases. including asthma, allergies and eczema, and it is not uncommon for many or some of these diseases affect a person. Studies suggest that rubbing the eyes vigorously may contribute to the progression of keratoconus, and patients should be discouraged from this practice.

What is Keratoconus?

What is Keratoconus?

Keratoconus or conical cornea is a disorder of the human eye which rarely causes blindness but can significantly interfere with vision. It is a condition in which the normally round cornea becomes distorted and develops a cone-shaped prominence. Since the cornea is the main lens of the eye, vision decreased significantly at the deforming in this way. The progression of keratoconus is usually slow and can stop at any stage: from mild to severe. If the keratoconus progresses, the cornea bulges and thins becoming irregular and sometimes forming scars.

Keratoconus is a non-inflammatory degenerative disease of the eye in which structural changes in the cornea to become thinner and change to a more conical shape (ectasia) that its normal gradual curve. Keratoconus can cause substantial distortion of vision, with multiple images, streaking and sensitivity to light all often reported by patients. Keratoconus is the most common corneal dystrophy, affecting one person in a thousand, it seems to occur in populations worldwide, although some ethnic groups have a higher prevalence than others. It is usually diagnosed in young patients and presents its most severe in the second and third decade of life.

Keratoconus can be treated in Los Angeles .

Intacs in beverly hills

LASIK  is omnipresent in los angeles. Some of the top lasik doctors can be found in beverly hills and los angeles. Where is the help for keratoconus patients? Dont worry, some of the trusted keratoconus surgeons are in beverly hills. Amongst them is Rajesh Khannna, MD. He is board certified by the American Board of Ophthalmology. He is specially trained in corneal diseases including keratoconus. In his beverly hills office he helps people from all over los angeles. Using advanced diagnostic equipment like topography and pachymetry he can diagnose early stages of keratoconus. And than depending on what’s best for the patient he can suggest either special contact lenses, intacs or corneal transplant